1. Signaling Pathways
  2. Cell Cycle/DNA Damage
  3. DNA Stain

DNA Stain

There are several different stains that can be used to visualize and photograph DNA after separation by gel electrophoresis. Molecules of the dye adhere to DNA strands and fluoresce under UV light, showing where the bands are within the gel.

Hoechst stains are part of a family of blue fluorescent dyes used to stain DNA.There are three related Hoechst stains: Hoechst 33258, Hoechst 33342, and Hoechst 34580. The dyes Hoechst 33258 and Hoechst 33342 are the ones most commonly used and they have similar excitation/emission spectra.

DNA Stain Related Products (75):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-135413A
    Sulfo-CY5-NHS ester potassium
    MeCY5-NHS ester (potassium) is a reactive dye and can be used for labeling protein nucleic acid.
    Sulfo-CY5-NHS ester potassium
  • HY-W110781
    Basic Blue 20
    Basic Blue 20 is a very convenient red-emitting DNA stains. Basic Blue 20 has relatively narrow excitation and emission spectra, with peaks at 633 and 677 nm, respectively. Basic Blue 20 also has a very high resistance to photobleaching.
    Basic Blue 20
  • HY-D1408
    DMTr-4'-Me-U-CED-TBDMS phosphoramidite
    DMTr-4'-Me-U-CED-TBDMS phosphoramidite (DMTr-4'-Methyluridine-CED-TBDMS phosphoramidite), a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics, RNA aptamers, and ribozymes for elucidating RNA structure. DMTr-4'-Me-U-CED-TBDMS phosphoramidite represents a probe with wide utility for elucidation of RNA structure.
    DMTr-4'-Me-U-CED-TBDMS phosphoramidite
  • HY-162568
    7-tert-Butylfascaplysin
    7-tert-Butylfascaplysin (7-TB) is a derivative of Fascaplysin (HY-112328), that can be isolated from Fascaplysinopsis sp.. 7-tert-Butylfascaplysin induces replication stress, leads to toxic DNA double-strand breaks and apoptosis-like cell death, and thus exhibits cytotoxicity in cancer cells in nanomolar levels. 7-tert-Butylfascaplysin exhibits DNA intercalating activity with EC50 of 3.2 μM.
    7-tert-Butylfascaplysin
  • HY-16189
    Elliptinium acetate
    Modulator
    Elliptinium acetate (NSC 264137) is a DNA intercalating agent that is highly cytotoxic to L1 210 cells and covalently binds to nucleic acids from L1210 cells. Elliptinium acetate can be used in cancer research, particularly in metastatic breast cancer.
    Elliptinium acetate
  • HY-W012642A
    2-Aminopurine dihydrochloride
    2-Aminopurine dihydrochloride is a fluorescent analog of guanosine. 2-Aminopurine dihydrochloride can be used as a fluorescence probe for nucleic acid structure and dynamics. Incorporating 2-Aminopurine dihydrochloride into DNA quenches its fluorescence.
    2-Aminopurine dihydrochloride
  • HY-D1079
    EDANS sodium
    EDANS sodium is a potent fluorogenic substrates. EDANS sodium is a donor for FRET-based nucleic acid probes and protease substrates. EDANS sodium is often paired with DABCYL or DABSYL. The optimal absorbance and emission wavelengths of EDANS sodium are λabs = 336 nm and λem = 490 nm respectively.
    EDANS sodium
  • HY-D1686
    Biotin-16-UTP
    Biotin-16-UTP is an active substrate for RNA polymerase. Biotin-16-UTP can replace UTP in the in vitro transcription reaction for RNA labeling.
    Biotin-16-UTP
  • HY-D1660
    Acridine homodimer
    Acridine homodimer (NSC 219743), acridine dimer, is a fluorescence dye. Acridine homodimer emits a blue-green fluorescence when bound to DNA. Acridine homodimer has extremely high affinity for AT-rich regions of nucleic acids, can be used for chromosome banding.
    Acridine homodimer
  • HY-161164
    Tricyclic cytosine tC
    Tricyclic cytosine tC is a fluorescent base analogue that can be used as a fluorescent probe in nucleic acid-containing systems. The excitation wavelength is 385 nm and the emission wavelength is 505 nm.
    Tricyclic cytosine tC
  • HY-W094755
    1-Nitropyrene
    1-Nitropyrene is a DNA probe whose metabolites can form nucleic acid adducts with DNA.
    1-Nitropyrene
  • HY-D1411
    DMTr-4'-CF3-5-Me-U-CED phosphoramidite
    DMTr-4'-CF3-5-Me-U-CED phosphoramidite (DMTr-4'-CF3-5-Methyluridine-CED phosphoramidite), the modified oligodeoxynucleotide (ODN), is a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA research.
    DMTr-4'-CF3-5-Me-U-CED phosphoramidite
  • HY-B1953R
    Thiacloprid (Standard)
    Inhibitor
    Thiacloprid (Standard) is the analytical standard of Thiacloprid. This product is intended for research and analytical applications. Thiacloprid, a chloronicotinyl insecticide, is targeted chiefly to control aphid pest species in orchards and vegetables. Thiacloprid destabilizes DNA. Thiacloprid changes the structure and stability of DNA through binding into the minor groove by hydrophobic or hydrogen interactions.
    Thiacloprid (Standard)
  • HY-D0829
    3,6-Dichlorotrimellitic anhydride
    3,6-Dichlorotrimellitic anhydride is the key precursor that is used for preparing a variety of dichlorinated fluoresceins and rhodamines such as TET and HEX.
    3,6-Dichlorotrimellitic anhydride
  • HY-W142395S
    6-TAMRA-d12 free acid
    6-TAMRA-d12 free acid is a deuterated-labeled 6-TAMRA, which is widely used in the preparation of fluorescent antibodies and as a fluorescent group for immunohistochemical avidin derivatives.
    6-TAMRA-d<sub>12</sub> free acid